Off-label use of medicines in South Africa: a review

Abstract Background Off-label use of medicinal products has become an important part of mainstream and legitimate medical practice worldwide.This practice is common in oncology, obstetrics, paediatrics, and in the management of infectious diseases (notably HIV), and inflammatory conditions as well Apparel as in rare and/or orphan diseases.However,

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Spatio-temporal monitoring of vegetation phenology in the dry sub-humid region of Nigeria using time series of AVHRR NDVI and TAMSAT datasets

Time series data are of great importance for monitoring vegetation phenology in the dry sub-humid regions where change in land cover has influence on biomass productivity.However few studies have inquired into examining the impact of rainfall and land cover change on vegetation phenology.This study explores Seasonal Trend Analysis (STA) approach in

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Interferon alpha therapy for hepatitis C: treatment completion and response rates among patients with substance use disorders

Abstract Background Individuals with substance use disorders (SUDs) are at increased risk for hepatitis C viral infection (HCV), and few studies have explored their treatment responses empirically.The objective of this study was to assess interferon alpha therapy (IFN) completion and response rates among patients with HCV who had a history of comor

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Potential allergenicity of commonly sold high SPF broad spectrum sunscreens in the United States; from the perspective of patients with autoimmune skin disease

Background: Lack of established criteria for sunscreen product recommendations and potentially allergenic ingredients in sunscreens pose an issue for physicians and patients with autoimmune skin conditions.Objective: We reviewed cardigans popular sunscreens for effectiveness and potential allergenicity for recommendation and use in the autoimmune s

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